Evolutionary Systems Biology Group http://esbg.biology.gatech.edu/lab Mon, 23 Nov 2009 17:58:01 +0000 http://wordpress.org/?v=2.7.1 en hourly 1 March 25th http://esbg.biology.gatech.edu/lab/?p=252 http://esbg.biology.gatech.edu/lab/?p=252#comments Tue, 10 Mar 2009 17:46:26 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=252 hotopp-et-al-2006

jolley-et-al-2005

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=252 Wednesday March 4th http://esbg.biology.gatech.edu/lab/?p=240 http://esbg.biology.gatech.edu/lab/?p=240#comments Fri, 27 Feb 2009 17:59:38 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=240 “The Population Biology of Neisseria meningitidis: Implications for Meningococcal Disease, Epidemiology and Control.”

frosh-and-maiden-chapter-2

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=240 Feb 18, 2009 http://esbg.biology.gatech.edu/lab/?p=233 http://esbg.biology.gatech.edu/lab/?p=233#comments Mon, 16 Feb 2009 16:57:36 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=233 “Use of Variable-Number Tandem Repeats To Examine Genetic Diversity of Neisseria meningitidis”

Yazdankhah et al 2005.pdf

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=233 November 20th http://esbg.biology.gatech.edu/lab/?p=201 http://esbg.biology.gatech.edu/lab/?p=201#comments Tue, 18 Nov 2008 15:57:08 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=201 This week we will be looking at association mapping in bacteria, especially meningococcus.  The Falush paper is a short review article that focuses on the Bille 2005 paper.  The Bille paper investigates a repeat element that is traced back to an integrated bacteriophage.

falush_2006_trends-in-microbiology

bille05

Questions to help you

What is a bacteriophage?  Inverted repeat element?
How do the authors test to see if the sequence of interest is really derived from a bacteriophage?

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=201 October 23 http://esbg.biology.gatech.edu/lab/?p=184 http://esbg.biology.gatech.edu/lab/?p=184#comments Thu, 16 Oct 2008 19:08:07 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=184 Swartley et al describe capsule switching in Neisseria meningitidis.

swartley-capsule-switching

pnas-1997-jan941-271-6-all-figures

Major questions to answer

  • What is capsule switching?
  • What is the mechanism behind it?
  • How did the authors confirm capsule switching had occurred?
  • Why is it advantageous for Neisseria meningitidis to undergo capsule switching?
  • Why is the capsule itself advantageous?
]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=184 October 2, 2008 http://esbg.biology.gatech.edu/lab/?p=165 http://esbg.biology.gatech.edu/lab/?p=165#comments Thu, 25 Sep 2008 14:55:47 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=165 Our paper for the next meeting is below, and I’ll have some basic questions to help guide you by next week.

schoen-et-al

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=165 Combinatorial Patterns of Histone Modifications… http://esbg.biology.gatech.edu/lab/?p=161 http://esbg.biology.gatech.edu/lab/?p=161#comments Tue, 23 Sep 2008 15:22:36 +0000 Ahsan http://esbg.biology.gatech.edu/lab/?p=161 Hey guys, please read this paper for this week.

ng154

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=161 September 18, 2008 http://esbg.biology.gatech.edu/lab/?p=177 http://esbg.biology.gatech.edu/lab/?p=177#comments Fri, 12 Sep 2008 20:05:06 +0000 Lee http://esbg.biology.gatech.edu/lab/?p=177 meningo_vaccine

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=177 Congratulations! http://esbg.biology.gatech.edu/lab/?p=6 http://esbg.biology.gatech.edu/lab/?p=6#comments Wed, 31 Oct 2007 17:31:13 +0000 Lee http://esbg.biology.gatech.edu/wordpress/?p=6 Congratulations to Jing, Mark and Sanil! Manuscript “Evaluating the protein coding potential of exonized transposable element sequences” is accepted for publication in Biology Direct.

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=6 Welcome Andrew and Lee! http://esbg.biology.gatech.edu/lab/?p=7 http://esbg.biology.gatech.edu/lab/?p=7#comments Mon, 20 Aug 2007 17:32:42 +0000 Lee http://esbg.biology.gatech.edu/wordpress/?p=7 The ESBG welcomes new Bioinformatics PhD students Andrew Conley and Lee Katz.

]]> http://esbg.biology.gatech.edu/lab/?feed=rss2&p=7